Research paper
Mozaffarian D, Pischon T, Hankinson SE, Rifai N, Joshipura K, Willett WC, Rimm EB. Dietary intake of trans fatty acids and systemic inflammation in women. Am J Clin Nutr. 2004 Apr;79(4):606-12. doi:10.1093/ajcn/79.4.606. PMID: 15051604. PMCID: PMC1282449.
Why we cite it
Provides direct epidemiological evidence linking trans fat intake to systemic inflammation in generally healthy women, identifying a biological mechanism for trans fat cardiovascular harm beyond lipid effects. The finding that industrial trans fat isomers (trans 18:1 and 18:2) but not ruminant trans fat (trans 16:1) were associated with inflammation supports the distinction between industrial and ruminant trans fats.
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