Holt-Lunstad et al. 2010

Research paper

Holt-Lunstad J, Smith TB, Layton JB. Social relationships and mortality risk: a meta-analytic review. PLoS Medicine. 2010;7(7):e1000316. doi:10.1371/journal.pmed.1000316. PMID: 20668659. PMCID: PMC2910600.

Why we cite it

A meta-analysis of social relationships and mortality risk. Across 148 studies and 308,849 participants it finds a 50% increased likelihood of survival for people with stronger social relationships, an effect that held across age, sex, initial health status, cause of death and follow-up period, and differed significantly by the type of social measurement. The paper places social connection above obesity and physical inactivity as a mortality risk factor. 3,809 citations (Europe PMC, 2026-08-31).

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