Research paper
Blundell J, de Graaf C, Hulshof T, Jebb S, Livingstone B, Lluch A, Mela D, Salah S, Schuring E, van der Knaap H, Westerterp M. Appetite control: methodological aspects of the evaluation of foods. Obes Rev. 2010 Mar;11(3):251-70. doi:10.1111/j.1467-789X.2010.00714.x
Why we cite it
Methodological reference for appetite research, developed through the ILSI Europe Task Force on Appetite Regulation and Energy Balance. Establishes the critical distinction between satiation (the process that terminates eating and controls meal size) and satiety (the process that inhibits further eating and maintains fullness after a meal), arguing that these require different experimental designs. Provides guidance on study design (within-subject repeated measures preferred, double-blind, balanced randomized treatment order using Williams design), statistical approaches (AUC or repeated measures analysis, baseline as ANCOVA covariate rather than change-from-baseline), and practical significance thresholds (8–10% differences). Addresses whether hunger alone can serve as a measure of appetite control (insufficient — must be interpreted in relation to actual intake). Framed as guidance for evaluating health claims about food effects on appetite, following PASSCLAIM principles. Referenced by 1 companion and 1 companion-review (3 total references).
DOI: 10.1111/j.1467-789X.2010.00714.x · PubMed 20122136 · Publisher