Research paper
Wiss DA, Avena N, Rada P. Sugar Addiction: From Evolution to Revolution. Frontiers in Psychiatry. 2018;9:545. doi:10.3389/fpsyt.2018.00545
Why we cite it
Comprehensive 2018 review by the Avena/Rada team (who produced the foundational animal model work in csa01) that broadens their earlier findings into an evolutionary and public health framework. Uniquely integrates the evolutionary mismatch perspective with detailed neurobiology (dopamine habituation, D2 receptor downregulation, acetylcholine opposition) and maps sugar's effects onto DSM-5 substance use disorder criteria. Adds human evidence (YFAS 2.0 prevalence) and developmental/epigenetic dimensions not in the earlier papers.