Moore et al. 2015

Research paper

Moore DR, Churchward-Venne TA, Witard O, Breen L, Burd NA, Tipton KD, Phillips SM. Protein ingestion to stimulate myofibrillar protein synthesis requires greater relative protein intakes in healthy older versus younger men. Journals of Gerontology Series A. 2015 Jan;70(1):57-62. doi:10.1093/gerona/glu103

Why we cite it

A retrospective analysis of the authors’ laboratory data on myofibrillar protein synthesis in healthy older (~71 years) and younger (~22 years) men given 0-40 g of high-quality protein as a single bolus. Synthesis reached a plateau after 0.40 ± 0.19 g/kg body mass in older men against 0.24 ± 0.06 g/kg in younger men (p = .055), and after 0.60 ± 0.29 against 0.25 ± 0.13 g/kg lean body mass (p < .01). The authors conclude that healthy older men "require a greater relative protein intake, in a single meal, than young men to maximally stimulate postprandial rates of MPS".

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