Research paper
Gosby AK, Conigrave AD, Lau NS, Iglesias MA, Hall RM, Jebb SA, Brand-Miller J, Caterson ID, Raubenheimer D, Simpson SJ. Testing protein leverage in lean humans: a randomised controlled experimental study. PLoS ONE. 2011;6(10):e25929.
Why we cite it
A controlled experimental test of the protein leverage hypothesis in lean humans. Demonstrates that diluting dietary protein from 15% to 10% of energy increases total intake by 12%, primarily through snacking, while increasing protein to 25% does not proportionally reduce intake — revealing an asymmetric leverage effect. This asymmetry is important for the project: it means that protein dilution in ultra-processed food environments reliably drives overconsumption, but simply adding protein may not fully reverse it.
DOI: 10.1371/journal.pone.0025929 · PubMed 22022472 · Publisher
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