Giugliano et al. 2006

Research paper

Giugliano D, Ceriello A, Esposito K. The effects of diet on inflammation: emphasis on the metabolic syndrome. Journal of the American College of Cardiology. 2006 Aug 15;48(4):677-85. doi:10.1016/j.jacc.2006.03.052. PMID: 16904534.

Why we cite it

Review in the *Journal of the American College of Cardiology* establishing the connection between dietary patterns and systemic inflammation, with emphasis on metabolic syndrome. Documents that Western diets high in refined starches, sugar, saturated/trans fats and low in antioxidants, fibre, and omega-3s activate the innate immune system through excessive proinflammatory cytokine production. Shows that "prudent" dietary patterns (fruits, vegetables, legumes, whole grains, fish) reduce inflammation. Relevant to companion 379 as the dietary framework connecting food choices to inflammatory outcomes.