Research paper
David LA, Maurice CF, Carmody RN, et al. “Diet rapidly and reproducibly alters the human gut microbiome.” Nature. 2014;505(7484):559-563. doi:10.1038/nature12820. PMID: 24336217.
Why we cite it
Provides a controlled experimental demonstration that short-term dietary change rapidly and reproducibly reshapes the human gut microbiome — within a single day of food reaching the distal gut. Establishes that diet overwhelms inter-individual variation in microbial gene expression, and that microbiome functional profiles switch between herbivorous and carnivorous patterns mirroring mammalian evolution. Critical evidence for the “24–48 hour microbiome shift” claim used in companion 451.
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