Grassi et al. 2008

Research paper

Grassi D, Desideri G, Necozione S, Lippi C, Casale R, Properzi G, Blumberg JB, Ferri C. Blood pressure is reduced and insulin sensitivity increased in glucose-intolerant, hypertensive subjects after 15 days of consuming high-polyphenol dark chocolate. J Nutr. 2008 Sep;138(9):1671-6. doi:10.1093/jn/138.9.1671. PMID: 18716168.

Why we cite it

Randomized crossover trial demonstrating that flavanol-rich dark chocolate (not chocolate generally) improves cardiovascular and metabolic markers in a high-risk population. The crossover design with isocaloric flavanol-free white chocolate as control isolates the effect of cocoa flavanols specifically. Relevant to the project’s treatment of dark chocolate as a food with genuine health benefits when quality (flavanol content) is considered.

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