Research paper
St-Onge MP, Gallagher D. Body composition changes with aging: the cause or the result of alterations in metabolic rate and macronutrient oxidation? Nutrition. 2010 Feb;26(2):152-5. doi:10.1016/j.nut.2009.07.004. PMID: 20004080. PMCID: PMC2880224.
Why we cite it
Review examining the bidirectional relationship between body composition changes and metabolic rate changes with ageing. Key insight: the age-related reduction in RMR is greater than what body composition changes alone explain — organ metabolic rates themselves decline with age. In older adults, calculated RMR (from measured organ masses assuming stable metabolic rates) exceeded measured RMR by ~145 kcal/day, confirming that tissue-specific metabolic activity decreases independently of organ mass loss.
DOI: 10.1016/j.nut.2009.07.004 · PubMed 20004080 · Publisher
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