Cains et al 2017

Research paper

Cains S, Blomeley C, Kollo M, Rácz R, Burdakov D. Agrp neuron activity is required for alcohol-induced overeating. Nature Communications. 2017 Jan 10;8:14014. doi:10.1038/ncomms14014. PMCID: PMC5234092.

Why we cite it

Identifies, in mice, ”a biological factor required for appetite evoked by alcohol”: ethanol activates hypothalamic Agrp neurons, ”normally activated by starvation”, in what the authors call ”sustaining false ‘starvation alarms’ despite extracellular nutrient sufficiency”. This is a mouse study, run in single-housed mice ”to minimize social confounders” that human alcohol-eating research cannot exclude.

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