Olive Oil Evidence

Research supporting extra virgin olive oil for health.

What the evidence says

  • PREDIMED trial (~7,500 participants): Mediterranean diet with extra-virgin olive oil reduced cardiovascular events by ~30%. *Cite the 2018 corrected republication, not the 2013 original* — that paper was withdrawn over randomization protocol deviations affecting ~11% of participants, and the corrected version's sensitivity analyses confirmed the main findings[1]
  • Olive oil is rich in monounsaturated fat and polyphenols[1]
  • Olive oil intake associated with reduced risk of cardiovascular disease and mortality[2]
  • The cardiovascular benefit is specific to extra-virgin olive oil — each 10 g/day EVOO increase associated with 10% lower CVD risk, while refined/common olive oil showed no significant association[2]
  • Benefits seen especially for stroke prevention[1]
  • Extra-virgin olive oil contains oleocanthal, a phenolic compound that acts as a natural anti-inflammatory with a potency and profile "strikingly similar" to ibuprofen, inhibiting the same cyclooxygenase (COX) enzymes in the prostaglandin pathway[3]