Research paper
Tchernof A, Després JP. Pathophysiology of human visceral obesity: an update. Physiological Reviews. 2013 Jan;93(1):359-404. doi: 10.1152/physrev.00033.2011
Why we cite it
A comprehensive 46-page review in Physiological Reviews synthesizing the pathophysiology of visceral obesity. Establishes that visceral obesity reflects not merely excess intra-abdominal fat but a broader phenotype of dysfunctional subcutaneous adipose tissue expansion and ectopic triglyceride storage. Maps the full chain from visceral fat accumulation through proinflammatory cytokine release, portal vein fatty acid delivery to the liver, and downstream cardiometabolic consequences including dyslipidemia, insulin resistance, and inflammation.
DOI: 10.1152/physrev.00033.2011 · PubMed 23303913 · Publisher