Research paper
Paddon-Jones D, Westman E, Mattes RD, Wolfe RR, Astrup A, Westerterp-Plantenga M. Protein, weight management, and satiety. American Journal of Clinical Nutrition. 2008;87(5):1558S-1561S. doi:10.1093/ajcn/87.5.1558S
Why we cite it
Multi-expert review from a “Protein Summit” in AJCN setting out three ”Potential beneficial outcomes associated with protein ingestion”: increased satiety, increased thermogenesis, and maintenance of fat-free mass, the last ”in some individuals”. Provides specific trial data (6-month RCT, n = 60: nearly 2x fat loss with 25% vs 12% protein; 12-month study: -9.4 vs -5.9 kg) and mechanistic detail (it ”has been suggested” that protein turnover accounts for 68% of the acute thermogenic effect; net metabolizable energy of protein is 13 kJ/g vs 17 kJ/g Atwater factor). Also covers protein source differences (whey vs casein, animal vs plant) and compliance advantages. (Corrected 2026-09-10 from ”identifying three mechanisms by which moderate protein elevation aids weight management” and ”protein turnover accounts for 68% of acute thermogenic effect”, which dropped the review’s potential and its it has been suggested.)