Research paper
Calder PC, Ahluwalia N, Albers R, Bosco N, Bourdet-Sicard R, Haller D, Holgate ST, Jönsson LS, Latulippe ME, Marcos A, Moreines J, M’Rini C, Müller M, Pawelec G, van Neerven RJJ, Watzl B, Zhao J. A consideration of biomarkers to be used for evaluation of inflammation in human nutritional studies. British Journal of Nutrition. 2013 Jan;109(S1):S1-S34. doi:10.1017/S0007114512005119. PMID: 23343744.
Why we cite it
A 34-page supplement review (S1–S34) by seventeen authors, convened as an ”expert group” by the ILSI Europe Nutrition and Immunity Task Force in 2009 ”to attempt to identify robust and predictive markers, or patterns or clusters of markers, which can be used to assess inflammation in human nutrition studies” and ”to create a consensus for grading these biomarkers”. Key finding: there is no consensus on which single marker best represents low-grade inflammation or distinguishes between acute and chronic forms. Recommends combining multiple markers with kinetic analysis following standardised challenges as the most informative approach.
About the author
Philip C. Calder, PhD, DPhil, is Professor of Nutritional Immunology and Head of the School of Human Development and Health, Faculty of Medicine, University of Southampton. Highly Cited Researcher (Clarivate). Over 20 years of research on omega-3 and omega-6 fatty acids and their roles in immune and inflammatory responses. Former President of the International Society for the Study of Fatty Acids and Lipids (ISSFAL, 2009-2012), former President of the Nutrition Society (2016-2019), and President of the Federation of European Nutrition Societies (FENS, 2019-2023). Recipient of numerous awards including the Danone International Prize in Nutrition (2016), DSM Lifetime Achievement Award in Human Nutrition (2017), British Nutrition Foundation Prize (2015), and the Ralph Holman Lifetime Achievement Award from the American Oil Chemists’ Society (2015).
DOI: 10.1017/S0007114512005119 · PubMed 23343744 · Publisher