Trepanowski et al. 2018

Research paper

Trepanowski JF, Kroeger CM, Barnosky A, Klempel M, Bhutani S, Hoddy KK, Rood J, Ravussin E, Varady KA. Effects of alternate-day fasting or daily calorie restriction on body composition, fat distribution, and circulating adipokines: secondary analysis of a randomized controlled trial. Clin Nutr. 2018 Dec;37(6 Pt A):1871-1878. doi:10.1016/j.clnu.2017.11.018. PMID: 29258678.

Why we cite it

A secondary analysis (approximately 121 Semantic Scholar citations) of the landmark JAMA Internal Medicine RCT (Trepanowski et al. 2017) comparing ADF to daily CR in 100 obese adults over 24 weeks. Provides the most rigorous head-to-head evidence that both approaches preserve lean mass equally. Referenced by 1 k-file in this corpus.