Patterson & Sears 2017

Research paper

Patterson RE, Sears DD. Metabolic Effects of Intermittent Fasting. Annual Review of Nutrition. 2017 Aug 21;37:371-393. doi:10.1146/annurev-nutr-071816-064634

Why we cite it

Systematic MEDLINE review synthesizing the evidence on intermittent fasting across three regimen types — alternate-day fasting, modified fasting (5:2), and time-restricted feeding. Identifies three proposed mechanistic pathways (circadian biology, gut microbiome, modifiable lifestyle behaviors) and highlights the importance of nighttime eating elimination and prolonged nightly fasting intervals.