Research paper
Church TS, Martin CK, Thompson AM, Earnest CP, Mikus CR, Blair SN. Changes in weight, waist circumference and compensatory responses with different doses of exercise among sedentary, overweight postmenopausal women. PLoS ONE. 2009;4(2):e4515. doi:10.1371/journal.pone.0004515
Why we cite it
The DREW study — a large, rigorously supervised dose-response RCT demonstrating that exercise at moderate doses produces weight loss matching caloric predictions, but higher doses trigger significant compensation (~47% of expected weight loss negated). Critically shows that all exercise doses reduce waist circumference independent of weight change, supporting the project’s message that exercise benefits health even when the scale doesn’t move as expected.
DOI: 10.1371/journal.pone.0004515 · PubMed 19223984 · Publisher