Mattson et al 2017

Research paper

Mattson MP, Longo VD, Harvie M. Impact of intermittent fasting on health and disease processes. Ageing Research Reviews. 2017 Oct;39:46-58. doi:10.1016/j.arr.2016.10.005

Why we cite it

Comprehensive review of intermittent fasting's effects on health and disease across both animal and human studies. Distinguishes three IF patterns (IF, periodic fasting, time-restricted feeding), synthesizes animal longevity data, human RCT results for weight loss and metabolic markers, and identifies cellular mechanisms (mitochondrial health, autophagy, DNA repair). Complements caf03 (Mattson 2018) which focuses specifically on brain/neuroplasticity; this paper covers the broader health and disease landscape.